1000 Genomes Project
The International 1000 Genomes Project
The International Human Genome Project greatly promoted the development of technologies and researches in the field of genomics. The following International HapMap Project generated a genome-wide catalogue of common SNP variations, which revolutionized human genetic studies and has made possible discoveries in the latest few years of over 200 new genes that contribute to complex diseases such as diabetes, heart attack, etc. The great achievements of studies based on this resources proved to scientists the necessity for a even higher resolution genetic map that takes into account variants with frequencies below 5%, as well as other forms of human genetic variations, such as InDel (Insertion and deletion), CNV (Copy Number Variations), SV (Structure Variations) and etc.
The 1000 genomes project, launched in January 2008, is initiated by an international research consortium that aims to produce most detailed map of human genetic variation to support disease studies. Beijing Genomics Institute at Shenzhen (BGI-Shenzhen, China), The Wellcome Trust Sanger Institute (UK) and National Human Genome Research Institute (NHGRI, US), as the major supporters and co-initiators of this international project and will be responsible for sequencing the genomes of at least one thousand people from around the world. BGI is carrying out the sequencing of 3 Tb of Asian genomes and the corresponding bioinformatics interpretation part.
As other major human genome related projects, data from the 1000 Genomes Project will be made swiftly available to the worldwide scientific community through freely accessible public databases.