Team leader: Can Long
BGI Cloud Computing project aims at creating a software environment enabling users to make a large number of bioinformatics analyses, combined with smooth data management and excellent graphical viewing and output options. Our team puts efforts mainly on integrating self-developed powerful tools and efficient workflows of bioinformatics research, especially focusing tools optimized for the analysis of nucleotide sequences from next generation sequencing technology such as short oligo nucleotide alignment program (SOAP), De novo assembly tools et., into BGI workbench with friendly user interface. This bioinformatics platform will ensure both private and public research will implement the new sequencing technologies quicker and therefore, reap the benefits faster.
We are now focusing on introducing Solexa sequencing analysis service as below:
1. Tag-based mRNA profiling is a revolutionary approach for expression analysis that generates expression profiles for any transcript from any organism. Driven by Solexa Sequencing, tag-based mRNA profiling creates whole genome wide expression profiles by sequencing over 1 million cDNA tags per sample rather than employing hybridization techniques such as gene expression microarrays. We have developed a pipeline to analysis the sequencing data of this solution, which finally generate an expert report.
2. MIREAP is a program that identifies both known and novel miRNAs from deep sequenced small RNA libraries with additional criteria. We use a methodology including full consideration of miRNA biogenesis, sequencing depth, and structural features to improve the sensitivity and specificity of miRNA identification.